Actorise (Darbepoetin) Injection
Generic API Name: Darbepoetin. Generic Branded Name: Actorise Generic brand for Actorise (Darbepoetin) Injection is available in India. It is used in the treatment of anemia that may have occurred due to chronic kidney disease or chemotherapy. Actorise 40 Injection can be used for treating anemia that could have developed as a result of the chronic renal disease, or chemotherapy. It stimulates the bone marrow to create more red blood cells. Generic brands for Darbepoetin Injection Available in India Brand Name Actorise Generic Name Darbepoetin Strength 40mcg, 100mcg, 200mcg Manufacturer Cipla Ltd. Aark ,a licensed pharmaceutical distributor operating across India, serves as a stockist, agency, or wholesaler of generic API pharma products, including “Actorise (Darbepoetin) Injection” in Ind
About Actorise (Darbepoetin) Injection
Description Darbepoetin, sold under the brand name Actorise, It is licensed for the treatment of anemia caused by kidney failure or chemotherapy . Darbepoetin alfa binds to the erythropoietin receptor on erythroid progenitor cells, stimulating RBC production and differentiation. Darbepoetin alfa is a re-engineered form of erythropoietin containing 5 amino acid changes (N30, T32, V87, N88, T90) resulting in the creation of 2 new sites for N-linked carbohydrate addition. It stimulates erythropoiesis (increases red blood cell levels) by the same mechanism as rHuEpo (binding and activating the Epo receptor) and is used to treat anemia, commonly associated with chronic kidney failure and cancer chemotherapy. The medication was approved in September 2001, by the US Food and Drug Administration for treatment of anemia in patients with chronic kidney failure by intravenous or subcutaneous injection.[4] In June 2001, it had been approved by the European Medicines Agency for this indication as well as the treatment of anemia in cancer patients undergoing chemotherapy. List of available brand-name drugs in India for Darbepoetin alfa Injection Branded Generic Drugs for Darbepoetin alfa Injection : Actorise | Bionesp | Cresp | Daptobio | Darbecept | Darbilen | Derise | Zynesp NEWS / Updates Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Hematopoietic agents, 12th edition, 1071 – 1072. Amgen Europe BV, Electronic medicines compendium (EMC), [Revised on Feb 2021] [Accessed on 13th Aug 2021], https://www.medicines.org.uk/emc/files/pil.6958.pdf Anna Maria Libudzic-Nowak et al., Darbepoetin Alfa in Young Infants With Renal Failure: Single Center Experience, a Case Series and Review of the Literature, Sec. Pediatric Nephrology, Published on 18th Dec 2018, Accessed on 13th Aug 2022, https://www.frontiersin.org/articles/10.3389/fped.2018.00398/full Written By Mr. Sandeep Tomar (D. pharma) Last updated 26 Sep 2024 | 05:03 AM (IST)
